Title:
被験者における結腸直腸癌の確率を決定するための方法および装置
Document Type and Number:
Japanese Patent JP2011517941
Kind Code:
A
Abstract:
A method of determining a probability that a human test subject has colorectal cancer as opposed to not having colorectal cancer is disclosed. The method comprises, for each gene of a set of one or more genes selected from the group consisting of ANXA3, CLEC4D, IL2RB, LMNB1, PRRG4, TNFAIP6 and VNN1: determining a level of RNA encoded by the gene in blood of the test subject, thereby generating test data; providing positive control data representing levels of RNA encoded by the gene in blood of human control subjects having colorectal cancer, and providing negative control data representing levels of RNA encoded by the gene in blood of human control subjects not having colorectal cancer; and determining a probability that the test data corresponds to the positive control data and not to the negative control data, where the probability that the test data corresponds to the positive control data and not to the negative control data represents the probability that the test subject has colorectal cancer as opposed to not having colorectal cancer.
Inventors:
Jeong-Ching Liu
Samuel Chao
Samuel Chao
Application Number:
JP2011503520A
Publication Date:
June 23, 2011
Filing Date:
April 10, 2009
Export Citation:
Assignee:
Gene News Corporation
International Classes:
C12N15/09; C12Q1/68; G01N33/50; G16B5/20; G16B25/10; G16B25/20; G16B40/20; G16B40/30
Domestic Patent References:
| JP2007528704A | 2007-10-18 |
Foreign References:
| WO2007048074A1 | 2007-04-26 | |||
| EP1777523A1 | 2007-04-25 | |||
| WO2005054508A2 | 2005-06-16 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro