疾患を予防および処置するための方法および免疫調節核酸組成物

Japanese Patent JP2009540016

A

This invention relates to methods and compositions for treating or preventing disease comprising the administration of immune modulatory nucleic acids having one or more immune modulatory sequences (IMSs). The invention further relates to the means and methods for the identification of the IMSs for preventing or treating disease, more particularly the treatment and prevention of autoimmune or inflammatory diseases. The invention also relates to the treatment or prevention of disease comprising the administration of the immune modulatory nucleic acids alone or in combination with a polynucleotide encoding self-antigen(s), -proteins(s), -polypeptide(s) or -peptide(s). The present invention also relates to methods and compositions for treating diseases in a subject associated with one or more self-antigen(s), self-proteins(s), -polypeptide(s) or -peptide(s) that are present in the subject and involved in a non-physiological state.

Gehren Hideki
Leviten Michael
Solvason Nanette

JP2009515629A

November 19, 2009

June 13, 2007

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Bayhill Therapeutics Incorporated

A61K31/711; A61K48/00; A61P1/04; A61P1/06; A61P1/16; A61P3/10; A61P7/06; A61P9/00; A61P11/06; A61P13/02; A61P13/10; A61P17/00; A61P19/00; A61P19/02; A61P19/06; A61P21/00; A61P21/04; A61P25/00; A61P25/06; A61P27/02; A61P29/00; A61P31/20; A61P37/02; C12N15/09

JP2005527553A	2005-09-15
JP2006514933A	2006-05-18

JPN6012063098; ＡＲＴＨＲＩＴＩＳ　＆　ＲＨＥＵＭＡＴＩＳＭ Ｖｏｌ．４６，　Ｎｏ．８, 2002, ｐ．２２１９-２２２４
JPN6012063101; Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．１６９, 2002, ｐ．５５９０-５５９４

Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki

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