Title:
抗癌性化合物を製造するための方法と中間体
Document Type and Number:
Japanese Patent JP4074509
Kind Code:
B2
Abstract:
The present invention relates to methods and intermediates for preparing compounds of the formula 1 and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds, wherein R<1>, R<2> and R<15> are as defined herein. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. The present invention also relates to a method of preparing compounds of the formula 9 and the pharmaceutically acceptable salts and solvates thereof, wherein R<6>-R<10> and R<15> are as defined herein.
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Inventors:
Richard Shelton Learner
Timothy Norris
Dinos Paul Santafianos
Timothy Norris
Dinos Paul Santafianos
Application Number:
JP2002360742A
Publication Date:
April 09, 2008
Filing Date:
December 12, 2002
Export Citation:
Assignee:
Pfizer Products Inc.
OSI Pharmaceuticals Incorporated
OSI Pharmaceuticals Incorporated
International Classes:
C07D239/94; A01N43/54; A61K31/00; A61K31/33; A61K31/40; A61K31/498; A61K31/505; A61K31/517; A61P35/00; C07B61/00; C07D235/14; C07D239/70; C07D239/72; C07D239/74; C07D239/95; C07D401/00; C07D403/00; C07D405/00; C07D409/00; C07D413/00; C07D417/00; C07D419/04; C07D455/02; C07D471/04; C07D473/00; C07D475/00; C07D491/048; C07F7/08; C07F7/10; C22B3/04; C22B15/00; A61K; C07D
Domestic Patent References:
| JP10506633A |
Foreign References:
| US5747498 |
Other References:
GREEN, T.W. and WUTS, P.G.M.,Protective Groups in Organic Synthesis,JOHN WILEY & SONS, INC.,1991年,p.425-428
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami