抗ＥＲＢＢ３抗体治療に対する食道癌の応答を予測する方法およびキット

Title:

抗ＥＲＢＢ３抗体治療に対する食道癌の応答を予測する方法およびキット

Document Type and Number:

Japanese Patent JP7181290

Kind Code:

B2

Abstract:

Disclosed is a method for predicting whether the esophagus cancer is sensitive or resistant to a therapy using an ERBB3 inhibitor (i.e., an anti-ERBB3 antibody). Specifically, the method carries out prediction by measuring expression of the RNA level or protein level of a marker of at least one of SDC, PTGES, NCF2, NOXA1, CARD6, and GNAZ in a tumor sample.

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Inventors:

shwe james chung
Wang Jin
Gao Ya
Fu Fai Chung

Application Number:

JP2020520701A

Publication Date:

November 30, 2022

Filing Date:

June 12, 2018

Export Citation:

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Assignee:

Cambridge Life Sciences Limited

International Classes:

G01N33/68

Domestic Patent References:

JP2015501142A

Foreign References:

WO2016127220A1

Attorney, Agent or Firm:

Hayashi Kazuyoshi
Tetsuo Shiba
Takuya Saito
Mitsuru Iwaike
Kazuhiro Kosuga

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