Title:
許容可能な血清中テストステロン・レベルを信頼性高く達成するための方法及び医薬組成物
Document Type and Number:
Japanese Patent JP4680891
Kind Code:
B2
Abstract:
The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.
Inventors:
Hubler, Doris
Fricke, Sabine
Inkbelsen, Jan-Peter
Coons, Bilheim
Fricke, Sabine
Inkbelsen, Jan-Peter
Coons, Bilheim
Application Number:
JP2006506335A
Publication Date:
May 11, 2011
Filing Date:
March 15, 2004
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
A61K31/568; A61K9/00; A61K9/08; A61K31/56; A61K31/565; A61K31/57; A61K36/47; A61K47/14; A61K47/44; A61P5/24; A61P5/26; A61P15/00; A61P15/08; A61P15/10; A61P15/16; A61P19/10; A61P21/00; A61P25/24; A61P43/00; C07J1/00
Foreign References:
| US4181721 | ||||
| WO1995012383A1 |
Other References:
LE MANUEL MERCK DE DIAGNOSTIC ET THERAPEUTIQUE,米国,MERCK RESEARCH LABORATORIES,P2352-2356
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama