Title:
1,4,7-トリアザシクロノナンのコンジュゲート、斯かるコンジュゲートの二核金属錯体、並びに1,4,7-トリアザシクロノナン及びコンジュゲートの双方の使用の方法
Document Type and Number:
Japanese Patent JP2013525270
Kind Code:
A
Abstract:
Conjugates of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes with a variety of conjugating members are used in the formation of dinuclear metal complexes which bind to phosphate esters. By virtue of their conjugated forms, the complexes are incorporated into chromatographic media, affinity binding reagents, and dyes, which make the complexes useful in a wide range of assays, separations, and purifications. In addition, dinuclear metal complexes of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes that are not so conjugated are used in the detection of phosphate esters of biological species by either MALDI-TOF mass spectrometry or by dye displacement.
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Inventors:
Thomas Earl. Berkelman
Lisandra martin
Ryanon Jones
John Walker, The Second
Lisandra martin
Ryanon Jones
John Walker, The Second
Application Number:
JP2013500088A
Publication Date:
June 20, 2013
Filing Date:
March 09, 2011
Export Citation:
Assignee:
Bio - Rad Laboratories, Lee emissions Incorporated Rei tee de
International Classes:
C07D255/02; C07D405/14; C07D495/04; G01N21/78; G01N27/62; G01N30/88
Domestic Patent References:
| JP2005526487A | 2005-09-08 |
Other References:
JPN7014000972; Ｉｎｏｒｇ．Ｃｈｅｍ． ４２（２４）, 2003, ｐｐ．７７３７-７７４６
JPN7014000973; Ｉｎｏｒｇ．Ｃｈｅｍ． ３９（５）, 2000, ｐｐ．８８１-８９２
JPN7014000974; Ｉｎｏｒｇ．Ｃｈｅｍ． ３２（２０）, 1993, ｐｐ．４２７７-４２８３
JPN7014000975; Ｉｎｏｒｇ．Ｃｈｅｍ． ３７（１５）, 1998, ｐｐ．３７０５-３７１３
JPN7014000973; Ｉｎｏｒｇ．Ｃｈｅｍ． ３９（５）, 2000, ｐｐ．８８１-８９２
JPN7014000974; Ｉｎｏｒｇ．Ｃｈｅｍ． ３２（２０）, 1993, ｐｐ．４２７７-４２８３
JPN7014000975; Ｉｎｏｒｇ．Ｃｈｅｍ． ３７（１５）, 1998, ｐｐ．３７０５-３７１３
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei