Title:
METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
Document Type and Number:
Japanese Patent JP2022153467
Kind Code:
A
Abstract:
To provide methods and compositions for making targeted changes of a DNA sequence.SOLUTION: In various aspects and embodiments, methods and compositions are provided for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal or mammalian cell). In some aspects and embodiments, the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of target cell gene repair mechanisms, such as a DNA cutter.SELECTED DRAWING: Figure 1
Inventors:
Beatham, Peter Earl.
Gocal, Gregory F. W.
Scoopke, christian
Sauer, Noel
Pierce, james
Sega, Rosa, E.
Jolly Mosork
Gocal, Gregory F. W.
Scoopke, christian
Sauer, Noel
Pierce, james
Sega, Rosa, E.
Jolly Mosork
Application Number:
JP2022112955A
Publication Date:
October 12, 2022
Filing Date:
July 14, 2022
Export Citation:
Assignee:
Kibbs US LLC
Kibbs Europe Bee V.
Kibbs Europe Bee V.
International Classes:
C12N15/09; A01H1/00; A01H5/00; C12N1/13; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Domestic Patent References:
JP2009523418A | 2009-06-25 |
Foreign References:
WO2015139008A1 | 2015-09-17 | |||
WO2016007347A1 | 2016-01-14 |
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kamoto Takahashi
Nao Oda
Akiyo Iwahori
Kamoto Takahashi
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