Title:
二本鎖ＲＮＡによるグリコール酸オキシダーゼ（ＨＡＯ１）の特異的阻害に関する方法および組成物
Document Type and Number:
Japanese Patent JP7109416
Kind Code:
B2
Abstract:
The present invention relates to double-stranded nucleic acids (dsNAs) for use in the treatment of excessive urinary excretion of oxalate wherein administration of the dsNA results in reduction of HAO1 mRNA.
Inventors:
Brown, Bob, Dale
Dudek, Henrik, Tea
Dudek, Henrik, Tea
Application Number:
JP2019202937A
Publication Date:
July 29, 2022
Filing Date:
November 08, 2019
Export Citation:
Assignee:
DICERNA PHARMACEUTICALS, INC.
International Classes:
A61K31/713; A61K48/00; A61P13/04; A61P13/12; A61P43/00; C12N15/09; C12N15/113
Domestic Patent References:
| JP2017502668A | ||||
| JP2012512651A | ||||
| JP2013514089A |
Other References:
Database GenBank [online], Accessin No. NM_017545, 04-AUG-2013 uploaded, [retrieved on 2018-11-29]
HEPATOLOGY,2003年,38,1159-1166
Arh. Hig. Rada. Toksikol,2013年,64,609-630
HEPATOLOGY,2003年,38,1159-1166
Arh. Hig. Rada. Toksikol,2013年,64,609-630
Attorney, Agent or Firm:
Reiji Aihara