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Patent Searching and Data


Title:
METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS FOR TREATMENT AND MANAGEMENT OF CANCERS AND OTHER DISEASES
Document Type and Number:
Japanese Patent JP2017132817
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods of treating and preventing certain types of cancer, including primary and metastatic cancer, as well as cancers that are refractory or resistant to conventional chemotherapy.SOLUTION: A pharmaceutical for treating or preventing multiple myeloma comprises a therapeutically or prophylactically effective amount of the compound having the formula in the figure, 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione, or a pharmaceutically acceptable salt, solvate or stereoisomer thereof.SELECTED DRAWING: None

Inventors:
ZELDIS JEROME B
Application Number:
JP2017095838A
Publication Date:
August 03, 2017
Filing Date:
May 12, 2017
Export Citation:
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Assignee:
CELGENE CORP
International Classes:
A61K31/454; A61K45/00; A61K9/20; A61K9/48; A61K31/00; A61K31/198; A61K31/40; A61K31/4035; A61K31/425; A61K31/445; A61K31/515; A61K31/573; A61K35/12; A61K35/14; A61K35/28; A61K38/18; A61K38/20; A61K38/21; A61K41/00; A61K45/06; A61K51/00; A61P1/04; A61P1/16; A61P3/06; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P9/04; A61P9/10; A61P9/14; A61P11/00; A61P11/06; A61P11/16; A61P17/00; A61P17/02; A61P17/06; A61P17/10; A61P17/12; A61P19/02; A61P19/08; A61P19/10; A61P25/00; A61P27/02; A61P27/06; A61P27/10; A61P27/14; A61P29/00; A61P31/00; A61P31/04; A61P31/08; A61P31/10; A61P31/12; A61P31/18; A61P31/22; A61P33/00; A61P33/02; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D209/46; C07D401/04; C07J5/00
Domestic Patent References:
JP2005530784A2005-10-13
Foreign References:
WO2000059473A12000-10-12
Other References:
BLOOD, vol. 96, no. 9, JPN6008036305, 2000, pages 2943 - 2950
ANNU. REV. MED., vol. Vol.53, JPN6016015551, February 2002 (2002-02-01), pages 629 - 657
BIOMEDICINE AND PHARMACOTHERAPY, vol. Vol. 56, No. 3, JPN6009048965, 22 April 2002 (2002-04-22), pages 115 - 128
J IMMUNOL, vol. Vol.163, JPN6017026562, 1999, pages 380 - 386
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. Vol.9, JPN6017026564, 1999, pages 1625 - 1630
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Mami Hino
Yoshimitsu Maki
Yasuhito Suzuki