Title:
METHODS, COMPOUNDS AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID
Document Type and Number:
Japanese Patent JP2016034960
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods, compounds and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS), which is a therapeutic agent for treating AA amyloidosis, in a subject, preferably a human subject.SOLUTION: A method for treating or preventing disease comprises administering to a subject, preferably a human subject, in need thereof a 1,3-propanedisulfonic acid compound represented by formula I or a pharmaceutically acceptable salt or solvate compound thereof, or a composition containing the same. (R1 and R2 are each independently OR3, -NHC(O)R5, -NHC(NH)NHR5, -NH(C5-C10 heteroaryl), or the like; R3 and R5 are each independently H, C1-C12 alkyl, C-Calkenyl, C-Ccycloalkyl, C-Caryl, or the like.)SELECTED DRAWING: None
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Inventors:
KONG XIANQI
NIGEL LEVENS
ABDERRAHIM BOUZIDE
STEPHANE CIBLAT
RICHARD FRENETTE
JOHANNE RENAUD
NIGEL LEVENS
ABDERRAHIM BOUZIDE
STEPHANE CIBLAT
RICHARD FRENETTE
JOHANNE RENAUD
Application Number:
JP2015179480A
Publication Date:
March 17, 2016
Filing Date:
September 11, 2015
Export Citation:
Assignee:
BHI LTD PARTNERSHIP
International Classes:
C07C309/65; A61K31/18; A61K31/185; A61K31/255; A61K31/265; A61K31/27; A61K31/275; A61K31/341; A61K31/343; A61K31/39; A61K31/4155; A61K31/4178; A61K31/4402; A61K31/4406; A61K31/662; A61P3/04; A61P3/06; A61P3/10; A61P13/12; C07C303/30; C07C309/05; C07C311/06; C07C311/51; C07D213/64; C07D213/65; C07D231/12; C07D233/56; C07D307/00; C07D307/33; C07D327/00
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Attorney, Agent or Firm:
Ryoichi Takaoka
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