Title:
インスリン様成長因子Iを増強または阻害するための方法
Document Type and Number:
Japanese Patent JP4928443
Kind Code:
B2
Abstract:
The present invention provides αVβ3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same.
Inventors:
Clemmons, David Earl
Mail, Laura A
Mail, Laura A
Application Number:
JP2007511661A
Publication Date:
May 09, 2012
Filing Date:
May 06, 2005
Export Citation:
Assignee:
The University of North Carolina at Chapel Hill
International Classes:
A61K38/00; A61K38/16; A61K38/17; A61K39/395; A61L27/00; A61P9/10; A61P13/12; A61P19/08; A61P19/10; A61P25/00; A61P27/02; A61P35/00; A61P43/00; C07K7/04; C07K14/78; C07K16/28; G01N33/15; G01N33/50; G01N33/53
Other References:
XIONG,J.P. et al,Crystal structure of the extracellular segment of integrin alpha Vbeta3,Science,2001年,Vol.294, No.5541,p.339-45
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo