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Title:
組み換えパルボウィルスベクターの制御放出のための方法および配合物
Document Type and Number:
Japanese Patent JP2004501113
Kind Code:
A
Abstract:
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).

Inventors:
Monahan, Paul Yi
Samulsky, Richard Jay
Rabinowitz, Joseph Yee
Application Number:
JP2001587815A
Publication Date:
January 15, 2004
Filing Date:
June 01, 2001
Export Citation:
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Assignee:
University of North Carolina at Chapel Hill
International Classes:
C12N15/09; A61K9/16; A61K35/76; A61K38/00; A61K38/22; A61K38/48; A61K39/00; A61K47/32; A61K47/46; A61K48/00; A61L17/00; A61L27/54; A61P3/00; A61P5/00; A61P7/04; A61P7/06; A61P31/04; A61P35/00; A61P37/06; C12N9/64; C12N15/864; (IPC1-7): A61K48/00; A61K9/16; A61K35/76; A61K38/00; A61K38/22; A61K38/48; A61K39/00; A61K47/32; A61K47/46; A61P3/00; A61P5/00; A61P7/04; A61P7/06; A61P31/04; A61P35/00; A61P37/06
Foreign References:
WO2000024412A22000-05-04
WO1998041240A11998-09-24
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo