Title:
超音波システムを使用して脳腫瘍を治療するための方法及びキット
Document Type and Number:
Japanese Patent JP7053463
Kind Code:
B2
Abstract:
The present invention relates to a method for reducing an effective amount of Bevacizumab required for treating brain tumor. The present invention also provides a kit used for the aforesaid method. The present method adopts a combination strategy to combine Bevacizumab treatment with ultrasound exposure, which comprises at least the following steps: administering Bevacizumab to a subject; administering an ultrasound-response medium to said subject; and administering said subject with an ultrasound exposure. Specific effective amount of the Bevacizumab treatment and the ultrasound exposure were identified. The efficacy of conventional Bevacizumab treatment is significantly improved.
Inventors:
Liu, Hao-Lee
Chu, Po-Chun
Chan, Tin-Kuan
Way, Kuo-Chen
Chen, Ping-Yuen
Juan, Qi Eun-In
Chu, Po-Chun
Chan, Tin-Kuan
Way, Kuo-Chen
Chen, Ping-Yuen
Juan, Qi Eun-In
Application Number:
JP2018524762A
Publication Date:
April 12, 2022
Filing Date:
November 10, 2016
Export Citation:
Assignee:
NAVIFUS CO. LTD.
International Classes:
A61K39/395; A61K9/10; A61K9/14; A61K41/00; A61N7/02; A61P35/00; A61P43/00
Domestic Patent References:
| JP2014501918A | ||||
| JP2014504276A | ||||
| JP2011529039A |
Foreign References:
| WO2015047103A1 | ||||
| US7896821 | ||||
| US5752515 | ||||
| US20060241529 | ||||
| US20120095325 |
Other References:
Biochem.Biophys.Res.Commun.,2006年,Vol.340,p.1085-1090
Attorney, Agent or Firm:
Nao Terasaki