Title:
患者の脳のてんかん原性を変調する方法
Document Type and Number:
Japanese Patent JP7132555
Kind Code:
B2
Abstract:
The invention relates to modulating epileptogenicity in a brain of an epileptic patient. The method according to the invention comprises the steps of: providing a virtual brain; providing a model of an epileptogenic and of a propagation zones and loading said models in the virtual brain to create a virtual epileptic brain; acquiring data of the brain of the epileptic patient; identifying, in said data, a location of at least one possible epileptogenic zone; fitting the virtual epileptic brain against the data acquired from the epileptic patient and parametrizing said at least one possible epileptogenic zone in the virtual epileptic brain as an epileptogenic zone; and simulating, within the virtual epileptic brain, the effect of a network modulation mimicking a clinical intervention of the brain of the patient.
Inventors:
Jilsa, Victor
Bernard, Christoph
Bartholomew, Fabrice
Guy, Maxim
Bernard, Christoph
Bartholomew, Fabrice
Guy, Maxim
Application Number:
JP2019503484A
Publication Date:
September 07, 2022
Filing Date:
July 18, 2016
Export Citation:
Assignee:
University de Aix-Marseille (AMU)
Center National de Richerche Scientific (CNNRS)
Assistance Public-Opitox de Marseille (AP-HM)
Institute National de la Sante de la Shelche Medical (Intherm)
Center National de Richerche Scientific (CNNRS)
Assistance Public-Opitox de Marseille (AP-HM)
Institute National de la Sante de la Shelche Medical (Intherm)
International Classes:
A61B34/10; A61B5/055
Domestic Patent References:
| JP2014522283A |
Foreign References:
| US20140222738 | ||||
| US20160183828 |
Other References:
Viktor Jirsa,Seizurespread in virtual epileptic patient,IWSP7:Seventh International Workshop on Seizure Prediction,米国,2015年12月03日,URL:https://www.youtube.com/watch?v=Pw0VMmRmMEo
Viktor K Jirsa,Indivisualstructual connecctivity defines propagation networkus in partial epilepsy,Modeling seizure propagation,米国,2016年04月28日,5-16,URL:https://arxiv.org/ftp/arxiv/paperes/1604/1604.08508.pdf
Viktor K Jirsa,Indivisualstructual connecctivity defines propagation networkus in partial epilepsy,Modeling seizure propagation,米国,2016年04月28日,5-16,URL:https://arxiv.org/ftp/arxiv/paperes/1604/1604.08508.pdf
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kamoto Takahashi
Nao Oda
Akiyo Iwahori
Kamoto Takahashi
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