精製されたプロスタグランジンEシンターゼを調製するための方法

Japanese Patent JP2005526483

A

The invention provides purified preparations of prostaglandin E synthase (PGES), analogs and variants thereof, such as portions thereof, and fusion polypeptides comprising these. The invention also provides methods for obtaining these purified preparations; methods for identifying modulators of PGES, e.g., small molecules inhibiting or stimulating the activity of PGES; and methods for preparing prostaglandins. Nucleic acids encoding PGES polypeptides of the invention are also provided.

Jacobsen, Per-Joan
Weinander, Rolf
Morgenstern, Ralph
Rambalotto, Ralph H.

JP2003523607A

September 08, 2005

August 23, 2002

Click for automatic bibliography generation  

Pfizer Products Inc.
Karolinska Innovation Arbor

G01N33/50; A61K38/43; A61K45/00; A61P1/02; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P3/14; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/00; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P17/16; A61P19/00; A61P19/02; A61P19/06; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P25/04; A61P25/28; A61P27/02; A61P27/14; A61P29/00; A61P35/00; A61P35/04; A61P37/00; A61P37/08; A61P41/00; A61P43/00; B01J20/281; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/90; C12N15/09; C12P31/00; C12Q1/533; G01N30/14; G01N30/26; G01N30/88; G01N33/15; G01N33/68; (IPC1-7): C12N15/09; A61K38/43; A61K45/00; A61P1/02; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P3/14; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/00; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P17/16; A61P19/00; A61P19/02; A61P19/06; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P25/04; A61P25/28; A61P27/02; A61P27/14; A61P29/00; A61P35/00; A61P35/04; A61P37/00; A61P37/08; A61P41/00; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/90; C12P31/00; C12Q1/533; G01N30/14; G01N30/26; G01N30/48; G01N30/88; G01N33/15; G01N33/50; G01N33/68

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

Previous Patent: ＶＥＧＦＲ−１を発現する幹細胞の単離および動員

Next Patent: タンパク質修飾および維持分子