Title:
胆汁酸類を製造するための方法
Document Type and Number:
Japanese Patent JP6937893
Kind Code:
B2
Abstract:
The present disclosure provides methods of preparing cholic acid, deoxycholic acid, or chenodeoxycholic acid, an ester thereof, or a pharmaceutically or cosmetically acceptable salt thereof, and novel and useful synthetic intermediates, for example, as described for methods 1, 1A, 1B, 2, 3, 3A, and 4. The method can start with a plant derived steroid as a starting material, such as dehydroepiandrosterone (DHEA) or Acetyl-dehydroepiandrosterone (Ac-DHEA). Also provided are pharmaceutical or cosmetic compositions and uses thereof, which comprise one or more of cholic acid, deoxycholic acid, or chenodeoxycholic acid, an ester thereof, or a pharmaceutically or cosmetically acceptable salt thereof, which is of high purity, for example, free of animal derived impurities.
Inventors:
Riu, Tochun
Chain, Incho
Lee, Juno
Song, Yun Suk
Chain, Incho
Lee, Juno
Song, Yun Suk
Application Number:
JP2020505342A
Publication Date:
September 22, 2021
Filing Date:
August 03, 2018
Export Citation:
Assignee:
Meditox Inc.
International Classes:
C07J9/00; A61K8/63; A61K31/575; A61P3/00; A61P43/00; A61Q19/06; C07C33/05; C07C47/267; C07C49/513; C07C51/09; C07C59/11; C07C59/46; C07C67/31; C07C69/675; C07J1/00; C07J13/00
Foreign References:
US20130261317 | ||||
WO2008000068A3 |
Other References:
Database REGISTRY,1986年,RN 102399-65-5, Retrieved from STN international [online] ;retrieved on 25 February 2021
Database REGISTRY,1984年,RN 88378-76-1, Retrieved from STN international [online] ;retrieved on 25 February 2021
Database REGISTRY,2002年,RN 413597-22-5, Retrieved from STN international [online] ;retrieved on 25 February 2021
Database REGISTRY,1984年,RN 88378-76-1, Retrieved from STN international [online] ;retrieved on 25 February 2021
Database REGISTRY,2002年,RN 413597-22-5, Retrieved from STN international [online] ;retrieved on 25 February 2021
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation