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Title:
細胞中でタンパク質を発現するための方法および生成物
Document Type and Number:
Japanese Patent JP7436406
Kind Code:
B2
Abstract:
The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.

Inventors:
Angel, matthew
Rohde, Christopher
Application Number:
JP2021027831A
Publication Date:
February 21, 2024
Filing Date:
February 24, 2021
Export Citation:
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Assignee:
Factor Bioscience Inc.
International Classes:
C12N15/09; C12N5/10
Domestic Patent References:
JP2012509072A
Foreign References:
WO2012021632A2
WO2011154393A1
WO2011071931A2
WO2011159684A2
WO2012115454A2
Other References:
Proc. Natl. Acad. Sci. USA,2012年10月,Vol.109, No.43,p.17484-17489
PLOS Genetics,2012年08月,Vol.8, No.8,e1002861
Molecular Therapy,2008年,Vol.16, No.11,p.1833-1840
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito