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Title:
METHODS FOR TREATING MUSCULAR DYSTROPHY
Document Type and Number:
Japanese Patent JP2023099184
Kind Code:
A
Abstract:
To provide methods for treating muscular dystrophy.SOLUTION: The invention provides an AAV vector that expresses ANO5 gene, a method for inducing muscular regeneration, and an antioxidant therapy as a method for treating muscular dystrophy. A method for treating muscular dystrophy comprises administering to a subject in need thereof a therapeutically effective amount of a recombination AAV vector comprising: 1) a nucleic acid sequence at least 85% identical to the nucleic acid sequence of SEQ ID NO:1; 2) a nucleotide that hybridizes to the nucleotide sequence of SEQ ID NO:1 under stringent conditions; or 3) a fragment of the nucleic acid of SEQ ID NO:1 encoding a protein exhibiting ANO5 activity.SELECTED DRAWING: Figure 1

Inventors:
LOUISE RODINO-KLAPAC
Application Number:
JP2023076538A
Publication Date:
July 11, 2023
Filing Date:
May 08, 2023
Export Citation:
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Assignee:
RES INST NATIONWIDE CHILDRENS HOSPITAL
International Classes:
A61K31/7088; A61K31/122; A61K31/355; A61K31/385; A61K35/76; A61K45/00; A61K48/00; A61P21/00; A61P21/02; A61P39/06; A61P43/00
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto