Title:
メトトレキサートに基づく薬剤を投与することによって腫瘍性、血管原性、繊維芽細胞性及び/又は免疫抑制性眼球異常を治療する方法及びメトトレキサートに基づく薬剤を送達するための眼球イオン導入装置。
Document Type and Number:
Japanese Patent JP2004537551
Kind Code:
A
Abstract:
A method for treating neoplastic, angiogenic, fibroblastic, and/or immunosuppressive ocular irregularities of a living subject, comprising the steps of: providing a living subject, wherein the living subject includes an affected ocular area having a neoplastic, angiogenic, fibroblastic, and/or immunosuppressive irregularity; providing a methotrexate based medicament, wherein the methotrexate based medicament is capable of inhibiting DNA synthesis; associating a therapeutically effective concentration of the methotrexate based medicament with the affected ocular area of the living subject; and decreasing the neoplastic, angiogenic, fibroblastic, and/or immunosuppressive ocular irregularity of the living subject.
Inventors:
Stephen Warren
Stephen Hamilton
Stephen Hamilton
Application Number:
JP2003513568A
Publication Date:
December 16, 2004
Filing Date:
July 19, 2002
Export Citation:
Assignee:
IoMed Incorporated
International Classes:
C07D475/08; A61K31/50; A61K31/519; A61P9/00; A61P27/02; A61P35/00; A61P37/06; A61P43/00; (IPC1-7): A61K31/519; A61P9/00; A61P27/02; A61P35/00; A61P37/06; A61P43/00; C07D475/08
Attorney, Agent or Firm:
Kosaku Sugimura