METORPHAMIDE - NOVEL MORPHINE-LIKE PEPTIDE - UNIV LELAND STANFORD JUNIOR

Title:

METORPHAMIDE - NOVEL MORPHINE-LIKE PEPTIDE

Document Type and Number:

Japanese Patent JPS6036499

Kind Code:

A

Abstract:

A morphine-like amidated opioid octapeptide metorphamide having the structure Try-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2 has been isolated from bovine caudate nucleus extracts and synthesized by solid phase peptide synthesis methods. Metorphamide is thus far the only natural opioid peptide having a high mu -binding activity.

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Inventors:

JIYATSUKU DEIBUITSUDO BAACHIYA
ETSUKARUTO UEEBAA
KURISUTOFUAA JIYONASAN EBUANSU

Application Number:

JP13081784A

Publication Date:

February 25, 1985

Filing Date:

June 25, 1984

Export Citation:

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Assignee:

UNIV LELAND STANFORD JUNIOR

International Classes:

A61K38/00; A61K38/22; A61P25/04; C07K14/655; C07K1/20; C07K7/06; C07K14/575; C07K14/665; (IPC1-7): A61K37/02; C07K7/06; C07K99/00

Attorney, Agent or Firm:

Minoru Nakamura

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