Title:
MICELLE AQUEOUS SOLUTION OF LEVONANTRADOLE AND N-METHYLLEVONANTRADOLE AND LYOPHILIC VEHICLE FOR REDUCTIVE REGENERATION
Document Type and Number:
Japanese Patent JPS57136512
Kind Code:
A
Abstract:
A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also covered are pharmaceutically acceptable lyophile compositions prepared by the lyophilization of the aqueous micellar solutions.
Levonantradol and N-methyllevonantradol are analgetic and anti-emetic agents.
Inventors:
AAMANDO JIYOSEFU EIJIYUIAA
BIJIYAN RASADEI
BIJIYAN RASADEI
Application Number:
JP134282A
Publication Date:
August 23, 1982
Filing Date:
January 07, 1982
Export Citation:
Assignee:
PFIZER
International Classes:
A61K9/107; A61K31/47; A61K9/08; A61P1/08; A61P25/04; (IPC1-7): A61K9/08; A61K31/435
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