Title:
マイクロカプセル化技術及びその生成物
Document Type and Number:
Japanese Patent JP6566970
Kind Code:
B2
Abstract:
Inside-out gelation process to generate hydrogel microcapsules (aka microbeads). Methods of encapsulating biological material in the microbead 3-dimensional hydrogel matrix are described herein. The process generally comprises formation of a mixture of a hydrogel precursor compound, an optional biological material, and a divalent cation. The mixture is then combined with alginate, to generate an alginate shell around droplets of the mixture, followed by gelation of the hydrogel precursor core, and removal of the temporary alginate shell to yield self-sustaining microbeads.
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Inventors:
Carl Tick, Ramachandran
Steven, Michael, Harrington
Steven, Michael, Harrington
Application Number:
JP2016571014A
Publication Date:
August 28, 2019
Filing Date:
June 03, 2015
Export Citation:
Assignee:
LIKARDA,LLC
International Classes:
A61K9/16; A61K35/12; A61K35/39; A61K35/407; A61K35/545; A61K47/36; A61K47/42
Domestic Patent References:
| JP63146792A | ||||
| JP50046822A |
Other References:
Nature Materials,2013年,Vol.12,p.584-590
Attorney, Agent or Firm:
Noritaka Yokota
Enoki Yasutaka
Omori Miko
Enoki Yasutaka
Omori Miko