Title:
化学分析用マイクロ流体操作方法及び装置
Document Type and Number:
Japanese Patent JP4023819
Kind Code:
B2
Abstract:
A microchip laboratory system (10) and method provide fluidic manipulations for a variety of applications, including sample injection for microchip chemical separations. The microchip is fabricated using standard photolithographic procedures and chemical wet etching, with the substrate and cover plate joined using direct bonding. Capillary electrophoresis and electrochomatography are performed in channels (26, 28, 30, 32, 34, 36, 38) formed in the substrate. Analytes are loaded into a four-way intersection of channels by electrokinetically pumping the analyte through the intersection (40), followed by a switching of the potentials to force an analyte plug into the separation channel (34).
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Inventors:
Ramsey, Jay Michael
Application Number:
JP50661496A
Publication Date:
December 19, 2007
Filing Date:
August 01, 1995
Export Citation:
Assignee:
Lockheed Martin Energy Systems, Inc.
International Classes:
G01N27/447; G01N33/50; B01F13/00; B01J19/00; B01L3/00; C07B61/00; C12Q1/68; G01N30/16; G01N30/60; G01N37/00; G05D11/02; B29C65/00; B29C65/48; G01N30/02; G01N30/28; G01N30/38; G01N30/84
Domestic Patent References:
| JP4221764A |
Other References:
Carlo S. Effenhauser, Glass Chips High-Speed Capillary Electrophoresis Separations with Submicrometer Plate Heights, Analytical Chemistry, 1993年10月 1日, Vol.65,No.19, 2637-2642
Stephen C. Jacobson, Effects of Injection Schemes and Column Geometryon the Performance of Microchip Electrophoresis Dev, Analytical Chemistry, 1994年 4月 1日, Vol.66,No.7, 1107-1113
Stephen C. Jacobson, Open Channle Electrochromatography on a Microchip, Analytical Chemistry, 1994年 7月15日, Vol.66,No.14, 2369-2373
Stephen C. Jacobson, Effects of Injection Schemes and Column Geometryon the Performance of Microchip Electrophoresis Dev, Analytical Chemistry, 1994年 4月 1日, Vol.66,No.7, 1107-1113
Stephen C. Jacobson, Open Channle Electrochromatography on a Microchip, Analytical Chemistry, 1994年 7月15日, Vol.66,No.14, 2369-2373
Attorney, Agent or Firm:
Yuzo Yamazaki