Title:
β2 MICROGLOBULIN-DEFICIENT CELLS
Document Type and Number:
Japanese Patent JP2023073426
Kind Code:
A
Abstract:
To provide β2 microglobulin-deficient cells.SOLUTION: The invention provides isolated cells that comprise a genetically engineered disruption in a β2 microglobulin (Bβ2M) gene, the cells being human primate cells, the cells further comprising one or more polynucleotides capable of encoding a single chain fusion non-classical human leukocyte antigen (HLA) class I protein.SELECTED DRAWING: None
Inventors:
Russell, David W.
Hirata, Lori Kay.
Hirata, Lori Kay.
Application Number:
JP2023054810A
Publication Date:
May 25, 2023
Filing Date:
March 30, 2023
Export Citation:
Assignee:
THE UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
International Classes:
C12N5/10; A61K35/12; A61K35/28; A61K39/00; A61K39/39; A61K48/00; A61P37/04; A61P43/00
Attorney, Agent or Firm:
Makoto Onda
Hironobu Onda
Atsushi Honda
Miki Nakamura
Hironobu Onda
Atsushi Honda
Miki Nakamura
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