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Title:
MITOCHONDRION LOCALIZED FLUORESCENT COMPOUND
Document Type and Number:
Japanese Patent JP2017031095
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a fluorescent compound capable of labeling mitochondrion more easily with high sensitivity and specificity.SOLUTION: There is provided a fluorescent composition for fluorescent dyeing mitochondrion containing a compound represented by the formula (1) or a salt thereof. (1), where Rand Rare a halogen atom, a C1 to 10 alkyl group, a C1 to 10 alkoxy group, a C2 to 10 alkenyl group, C2 to 10 alkynyl group, C3 to 10 cycloalkyl group or a C4 to 10 cycloalkylalkyl group, Rto Rare H, a halogen atom, a C1 to 10 alkyl group, a C1 to 10 alkoxy group, a C2 to 10 alkenyl group, a C2 to 10 alkynyl group, a C3 to 10 cycloalkylalkyl group or a C4 to 10 cycloalkylalkyl group, n1 is 0 to 5, n2 is 0 to 5, A is a fluorescent organic group, m1 and m2 are 0 or 1 and m1+m2=1.SELECTED DRAWING: None

Inventors:
ABE TAKAAKI
HAYASHI KENICHIRO
Application Number:
JP2015152489A
Publication Date:
February 09, 2017
Filing Date:
July 31, 2015
Export Citation:
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Assignee:
UNIV TOHOKU
KAKE EDUCATIONAL INST
International Classes:
C07F5/02; C07D209/18; C09K11/06; G01N21/64; G01N33/15; G01N33/50
Domestic Patent References:
JP2008536947A2008-09-11
Foreign References:
WO2014080640A12014-05-30
CN102735667A2012-10-17
KR100484748B1
Other References:
INDIAN J. CHEM, vol. 20B(5), JPN6019013017, 1981, pages 424 - 426, ISSN: 0004132577
TOHOKU J. EXP. MED., vol. 236, JPN6019013018, 2015, pages 225 - 232, ISSN: 0004132578
J. CHEM. SOC. PAK., vol. 9(1), JPN6019013019, 1987, pages 1 - 10, ISSN: 0004132579
J. CHEM. PHARM. RES., vol. 3(3), JPN6019013020, 2011, pages 248 - 259, ISSN: 0004132580
EGYPT. J. CHEM., vol. 45(4), JPN6019013021, 2002, pages 767 - 776, ISSN: 0004132581
J. ORG. CHEM., vol. 78, JPN6019013022, 2013, pages 9153 - 9160, ISSN: 0004014930
ANALYST, vol. 138(20), JPN6019013023, 2013, pages 6091 - 6096, ISSN: 0004014931
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Arima Masahiro