Title:
ミトコンドリアを標的とする抗酸化剤として使用されるミトキノン誘導体
Document Type and Number:
Japanese Patent JP4648319
Kind Code:
B2
Abstract:
This invention relates to pharmaceutically acceptable amphiphilic antioxidant compounds, compositions and dosage forms comprising said compounds and methods and uses reliant on said compounds. The exemplified compounds are all mitoquinone derivatives, being methoxyphenyl alkyl triphenylphosphonium or methoxy dioxocyclohexadiene alkyl triphenylphosphonium derivatives. The compounds, compositions, dosage forms, uses and methods are useful in, for example, the treatment of diseases or conditions associated with oxidative stress.
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Inventors:
Taylor, kenneth martin
Smith, robin
Smith, robin
Application Number:
JP2006523805A
Publication Date:
March 09, 2011
Filing Date:
August 23, 2004
Export Citation:
Assignee:
Antipodes Pharmaceuticals, Inc.
International Classes:
C07F9/54; A61K31/66; A61K47/40; A61K47/48; A61P25/14; A61P25/16; A61P25/28; A61P43/00; C07C309/04; C07C309/30
Domestic Patent References:
| JP3074395A | ||||
| JP2003520827A | ||||
| JP2002104922A |
Foreign References:
| US6331532 | ||||
| WO2003065882A1 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazumi Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazumi Nakamura