Title:
アルキルアンモニウムＥＤＴＡ塩を含む混合物及び製剤
Document Type and Number:
Japanese Patent JP7138626
Kind Code:
B2
Abstract:
The present invention relates to pre-formulations comprising:a) at least one di-acyl lipid;b) at least one phospholipid;c) at least one biocompatible, organic solvent;d) an alkyl ammonium EDTA salt; ande) at least one somatostatin receptor agonist;wherein the pre-formulation has a water content in the range of 0 to 1.0 wt %.The invention further relates to methods of treatment comprising administration of such pre-formulations, to pre-filled administration devices and kits containing the formulations, to the use of an alkylammonium EDTA salt to reduce the decomposition of the lipid components and/or any active agent contained within the pre-formulation.
Inventors:
Barow Sukas, Justa
Nister, Catalin
Johnson, Marx
Nister, Catalin
Johnson, Marx
Application Number:
JP2019516405A
Publication Date:
September 16, 2022
Filing Date:
September 26, 2017
Export Citation:
Assignee:
Kamurus AB
International Classes:
A61K47/14; A61K8/34; A61K8/37; A61K8/41; A61K8/46; A61K8/55; A61K8/64; A61K9/08; A61K9/10; A61K38/08; A61K38/26; A61K45/00; A61K47/10; A61K47/18; A61K47/20; A61K47/24; A61P1/12; A61P1/18; A61P3/04; A61P5/14; A61P5/48; A61P7/04; A61P9/10; A61P35/00; A61Q19/00
Domestic Patent References:
| JP2012500787A | ||||
| JP2014520090A | ||||
| JP2015520762A | ||||
| JP2008501676A | ||||
| JP2016504353A |
Foreign References:
| WO2012160212A1 |
Other References:
Biochem. J.,1978年,Vol.169,pp.697-701
Attorney, Agent or Firm:
Patent business corporation Ikeuchi and Partners