Title:
Ｍｎｋ阻害薬およびそれに関連する方法
Document Type and Number:
Japanese Patent JP6615797
Kind Code:
B2
Abstract:
The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, W, W, Y andare as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well as methods for utilizing the compounds of Formula I and the pharmaceutically acceptable compositions of Formula I compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.
Inventors:
Siegfried H Like
Paul A. Splengerer
Stephen e webber
Alan Shin Shan
Justin Thomas Ernest
Paul A. Splengerer
Stephen e webber
Alan Shin Shan
Justin Thomas Ernest
Application Number:
JP2016575379A
Publication Date:
December 04, 2019
Filing Date:
June 24, 2015
Export Citation:
Assignee:
Effector Therapeutics, Incorporated
International Classes:
C07D471/04; A61K31/506; A61K31/519; A61K31/52; A61K31/551; A61P35/00; A61P35/02; A61P43/00; C07D213/81; C07D471/10; C07D471/20; C07D491/20; C07D495/20; C07D519/00
Domestic Patent References:
| JP2009542749A |
Foreign References:
| WO2014044691A1 | ||||
| WO2013174743A1 | ||||
| WO2016096721A1 | ||||
| WO2002098428A1 |
Other References:
J. Med. Chem.,2010年,53,6618-6628
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tsuyoshi Sato
Hiroshi Yamazaki
Tsuyoshi Sato