Title:
MODIFIED FACTOR VII
Document Type and Number:
Japanese Patent JP2003289890
Kind Code:
A
Abstract:
To provide a new anticoagulation factor of a modified factor VII useful as an anticoagulant.
The modified factor VII has at least one modification substantially inhibiting the ability of the factor VII activating a plasma factor X or IX in the active center. The anticoagulant comprises the modified factor VII together with a carrier acceptable as a medicine.
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Inventors:
BERKNER KATHLEEN L
PETERSEN LARS C
PETERSEN LARS C
Application Number:
JP2003118571A
Publication Date:
October 14, 2003
Filing Date:
February 28, 1992
Export Citation:
Assignee:
ZYMOGENETICS INC
NOVO NORDISK AS (DK)
NOVO NORDISK AS (DK)
International Classes:
A61K31/136; A61K38/43; A61K38/55; A61K45/00; A61P7/02; A61P9/10; A61P43/00; C07K14/745; C12N5/10; C12N9/64; C12N15/09; C12N15/57; A61K38/00; C12R1/91; (IPC1-7): C12N15/09; A61K31/136; A61K38/43; A61K38/55; A61K45/00; A61P7/02; A61P9/10; A61P43/00; C12N5/10
Attorney, Agent or Firm:
Takashi Ishida (2 outside)