MODIFIED STEM CELL MEMORY T CELLS, METHODS OF MAKING THE SAME, AND METHODS OF USING THE SAME

Title:

MODIFIED STEM CELL MEMORY T CELLS, METHODS OF MAKING THE SAME, AND METHODS OF USING THE SAME

Document Type and Number:

Japanese Patent JP2021191312

Kind Code:

A

Abstract:

To provide a method of producing modified stem memory T cells (e.g. CAR-T cells) for administration to a subject as, for example an adoptive cell therapy, wherein the disclosure provides a solution to the following long-felt but unmet need: there has been a long-felt but unmet need in the art for a method of producing modified stem-cell memory T cells for administration to a subject as, for example, an adoptive cell therapy.SOLUTION: Unlike traditional biological preparation and chemotherapeutics, modified-T cells of the disclosure possess the capacity to rapidly reproduce upon antigen recognition, thereby potentially obviating the need for repeat treatments.SELECTED DRAWING: None

Inventors:

ERIC OSTERTAG
DEVON SHEDLOCK

Application Number:

JP2021156988A

Publication Date:

December 16, 2021

Filing Date:

September 27, 2021

Export Citation:

Click for automatic bibliography generation Help

Assignee:

POSEIDA THERAPEUTICS INC

International Classes:

C12N5/10; A61K35/17; A61K35/76; A61K38/20; A61K38/43; A61K38/47; A61K39/02; A61K39/12; A61K39/395; A61K48/00; A61P31/04; A61P31/12; A61P35/00; A61P43/00; C12N5/0783; C12N15/10; C12N15/12; C12N15/13; C12N15/54; C12N15/62

Domestic Patent References:

JP2005528088A	2005-09-22
JP2006508692A	2006-03-16
JP2019528760A	2019-10-17

Foreign References:

WO2016109410A2	2016-07-07
WO2014153470A2	2014-09-25
WO1995030413A1	1995-11-16

Other References:

PROTEIN ENGINEERING, DESIGN & SELECTION(2004),VOL.27, NO.10, P.419-429, JPN6020041902, ISSN: 0005077162

Attorney, Agent or Firm:

Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Tatsunori Ikeda

Previous Patent: Enhanced stem cell composition

Next Patent: Endoscope system and how to operate the endoscope system