Title:
MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Document Type and Number:
Japanese Patent JP2021138751
Kind Code:
A
Abstract:
To provide methods of treating CFTR-mediated diseases, such as cystic fibrosis.SOLUTION: The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions, treatment methods and kits thereof.SELECTED DRAWING: None
Inventors:
MARK THOMAS MILLER
COREY ANDERSON
VIJAYALAKSMI ARUMUGAM
BRIAN RICHARD BEAR
HAYLEY MARIE BINCH
JEREMY J CLEMENS
THOMAS CLEVELAND
ERICA CONROY
TIMOTHY RICHARD COON
BRYAN A FRIEMAN
PETER DIEDERIK JAN GROOTENHUIS
RAYMOND STANLEY GROSS
SARA SABINA HADIDA-RUAH
HARIPADA KHATUYA
PRAMOD VIRUPAX JOSHI
PAUL JOHN KRENITSKY
LIN CHUN-CHIEH
GULIN ERDOGAN MARELIUS
VITO MELILLO
MCCARTNEY JASON
GEORGIA MCGAUGHEY NICHOLLS
FABRICE JEAN DENIS PIERRE
SILINA ALINA
ANDREAS P TERMIN
JOHNNY UY
ZHOU JINGLAN
COREY ANDERSON
VIJAYALAKSMI ARUMUGAM
BRIAN RICHARD BEAR
HAYLEY MARIE BINCH
JEREMY J CLEMENS
THOMAS CLEVELAND
ERICA CONROY
TIMOTHY RICHARD COON
BRYAN A FRIEMAN
PETER DIEDERIK JAN GROOTENHUIS
RAYMOND STANLEY GROSS
SARA SABINA HADIDA-RUAH
HARIPADA KHATUYA
PRAMOD VIRUPAX JOSHI
PAUL JOHN KRENITSKY
LIN CHUN-CHIEH
GULIN ERDOGAN MARELIUS
VITO MELILLO
MCCARTNEY JASON
GEORGIA MCGAUGHEY NICHOLLS
FABRICE JEAN DENIS PIERRE
SILINA ALINA
ANDREAS P TERMIN
JOHNNY UY
ZHOU JINGLAN
Application Number:
JP2021096627A
Publication Date:
September 16, 2021
Filing Date:
June 09, 2021
Export Citation:
Assignee:
VERTEX PHARMA
International Classes:
C07D207/34; A61K31/40; A61K31/4035; A61K31/404; A61K31/415; A61K31/4155; A61K31/416; A61K31/4184; A61K31/4196; A61K31/421; A61K31/4245; A61K31/427; A61K31/437; A61K31/4418; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/47; A61K31/4709; A61K31/472; A61K31/4725; A61K31/473; A61K31/496; A61K31/4965; A61K31/497; A61K31/505; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P11/08; A61P29/00; A61P31/00; A61P31/04; A61P43/00; C07D209/42; C07D209/44; C07D213/73; C07D213/81; C07D213/82; C07D215/54; C07D217/26; C07D223/16; C07D231/12; C07D231/14; C07D231/56; C07D235/24; C07D239/34; C07D241/24; C07D249/10; C07D263/34; C07D401/04; C07D401/12; C07D401/14; C07D403/06; C07D403/10; C07D403/12; C07D405/04; C07D405/12; C07D405/14; C07D409/04; C07D409/12; C07D409/14; C07D413/14; C07D417/12; C07D417/14; C07D451/02; C07D471/04; C07D471/08; C07D487/08; C07D491/052; C07D491/08; C07D491/107
Domestic Patent References:
| JP6896619B2 | 2021-06-30 | |||
| JP2007511530A | 2007-05-10 | |||
| JP2011520785A | 2011-07-21 | |||
| JP2008524233A | 2008-07-10 |
Foreign References:
| WO2014071247A1 | 2014-05-08 | |||
| WO2010123822A1 | 2010-10-28 |
Attorney, Agent or Firm:
Michiko Matsutani
Yasushi Ochiai
Yasushi Ochiai