Title:
新生仔予防接種用変異ワクシニアウイルスアンカラ
Document Type and Number:
Japanese Patent JP5690214
Kind Code:
B2
Abstract:
The invention concern the use of a virus for the preparation of a medicament for the vaccination or treatment of a neonatal or prenatal animal, including a human, wherein the virus is capable of infecting the cells of the neonatal or prenatal animal, including a human, but not capable of being replicated to infectious progeny virus in the neonatal or prenatal animal, including a human. The virus is preferably a Modified Vaccinia Virus Ankara. In particular, the invention concerns the vaccination of neonates against infections with viruses belonging the same virus group than the virus used for vaccination. Moreover, the invention concerns the vaccination of neonates against antigens selected from foreign antigens and tumour antigens, wherein the tumour antigen and/or the foreign antigen are different from the antigens associated with the virus. The invention further concerns the use of viruses as defined above to increase the level of factors which activate dendritic cells or their precursor cells and/or to increase the number of dendritic cells or their precursor cells and/or to increase the production and/or cellular content of an interferon (IFN) or IL-12.
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Inventors:
チャプリン・ポール
ズーター・マーク
アッカーマン・マティアス
フランキーニ・マルコ
フォルシュテット・ザビーネ
ヘフティ・ハンス・ペーター
ズーター・マーク
アッカーマン・マティアス
フランキーニ・マルコ
フォルシュテット・ザビーネ
ヘフティ・ハンス・ペーター
Application Number:
JP2011115564A
Publication Date:
March 25, 2015
Filing Date:
May 24, 2011
Export Citation:
Assignee:
バヴァリアン・ノルディック・アクティーゼルスカブ
International Classes:
A61K39/12; A61K39/39; A61K35/76; A61K39/205; A61K39/21; A61K39/235; A61K39/245; A61K39/275; A61K39/285; A61P31/12; A61P31/14; A61P31/20; A61P31/22; A61P37/04; C12N7/00; A61K39/00
Attorney, Agent or Firm:
Mitsufumi Ezaki
Minoru Kajisawa
Yoshinori Uenishi
Ichiro Torayama
Minoru Kajisawa
Yoshinori Uenishi
Ichiro Torayama