Title:
変異ウイルス
Document Type and Number:
Japanese Patent JP2007511216
Kind Code:
A
Abstract:
An herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding an antisense to the squamous cell carcinoma related oncogene (asSCCRO); and an herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding a short interfering ribonucleic acid (siRNA) molecule that is capable of repressing or silencing expression of squamous cell carcinoma related oncogene (SCCRO) nucleic acid or polypeptide are disclosed together with methods for generation and applications of such viruses.
Inventors:
Brown, Suzanne, Moira
Dan, Paul
Sing, Bhubanesh
Gunley, Ian
Dan, Paul
Sing, Bhubanesh
Gunley, Ian
Application Number:
JP2006538967A
Publication Date:
May 10, 2007
Filing Date:
November 17, 2004
Export Citation:
Assignee:
Crusade Laboratories Limited
Sloan-Kettering Institute for Cancer Research
Brown, Suzanne, Moira
Dan, Paul
Sing, Bhubanesh
Gunley, Ian
Sloan-Kettering Institute for Cancer Research
Brown, Suzanne, Moira
Dan, Paul
Sing, Bhubanesh
Gunley, Ian
International Classes:
C12N7/00; A61K31/7088; A61K35/76; A61K39/00; A61K39/245; A61K39/39; A61K48/00; A61P35/00; C12N15/09; C12N15/113; C12N15/869; C12R1/93
Domestic Patent References:
| JP2003520789A | 2003-07-08 |
Foreign References:
| WO2002038805A2 | 2002-05-16 | |||
| WO2003068809A2 | 2003-08-21 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita