Ｎ－芳香族アミド系化合物及びその製造方法と用途

Japanese Patent JP7316362

B2

The present invention relates to general formulas (I) and (II) an N-aromatic amide compound and a preparation method therefor, a pharmaceutical composition and a pharmaceutical preparation containing the general formulas (I) and (II), and applications of the general formulas (I) and (II) in preparation of a drug for treating an androgen-related disease. The definitions of R₁, R₂, R₃, R₄, R₅, R₆, W₁, W₂, W₃, W₄, and W₅ in the general formulas are the same as those in the specification. The compound can be used alone or as a composition for treating various androgen-related diseases such as prostate cancer, prostatic hyperplasia, breast cancer, bladder cancer, and ovarian cancer, and further for the treatment of acne, hirsutism, alopecia, and other diseases.and

Kunihiro Yang
Yu Lijun
He Junze
Dan Meijuan

JP2021542244A

July 27, 2023

September 17, 2019

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SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD.

C07D209/08; A61K31/404; A61K31/4045; A61K31/415; A61K31/4439; A61P5/26; A61P13/08; A61P17/10; A61P17/14; A61P35/00; A61P43/00; C07D231/14; C07D231/16; C07D401/12

JP2018513182A
JP51082269A

CN107400088A

STN DATABASE REGISTRY [ONLINE],2012年08月08日,[retrieved on 20 Apr. 2022], RN 1387940-35-3, 1351698-66-2, 1351694-91-1, 1351679-21-4, 1299363-11-3, 1288359-74-9, 1287181-00-3, 1212244-79-5, 1212197-09-5, 1212149-39-7, 1212122-17-2, 1212114-43-6, 1212104-60-3, 1212089-89-8, 1212085-33-0
Journal of Labelled Compounds and Radiopharmaceuticals,2016年,Vol. 59,pp. 264-269
Advanced Synthesis & Catalysis,2018年,Vol. 360,pp. 1384-1388

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