Title:
N* Carboxyalkyl * ourie statin and its use
Document Type and Number:
Japanese Patent JP5933562
Kind Code:
B2
Abstract:
The present application relates to new derivatives of monomethylauristatin F, substituted on the N terminus by a carboxyalkyl group, processes for preparing these derivatives, their use for the treatment and/or prevention of diseases and to produce medication for the treatment and/or prevention of diseases, particularly hyperproliferative and/or angiogenic disorders such as cancer disorders, for example. Such treatments can occur as monotherapies or in combination with other medication or further therapeutic measures.
Inventors:
Lerchen, Hans-Georg
El Sheikh, Sheriff
Stolte-Ludwig, Beatrix
Golfia, sufen
Schumacher, Johann
Gunot, Marc Jean
Kurenz, Ursula
El Sheikh, Sheriff
Stolte-Ludwig, Beatrix
Golfia, sufen
Schumacher, Johann
Gunot, Marc Jean
Kurenz, Ursula
Application Number:
JP2013530690A
Publication Date:
June 15, 2016
Filing Date:
September 26, 2011
Export Citation:
Assignee:
Seattle Genetics, Inc.
International Classes:
C07K5/027; A61K38/00; A61K38/08; A61P35/00; C07K1/10
Domestic Patent References:
| JP2010523469A |
Foreign References:
| WO2007008848A1 |
Other References:
Bioconjugate Chemistry,2006年,Vol.17,p.114-124
ChemMedChem,2011年,Vol.6,p.54-59
ChemMedChem,2011年,Vol.6,p.54-59
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Previous Patent: NA reduction of a fiber light coupler
Next Patent: DATA RECORDER OF CASSETTE MAGNETIC TAPE
Next Patent: DATA RECORDER OF CASSETTE MAGNETIC TAPE