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Title:
ヒストンデアセチラーゼ阻害剤としての、三員環基でω位置換したN-ヒドロキシアミド、その調製方法、及び医薬組成物への使用
Document Type and Number:
Japanese Patent JP2008533088
Kind Code:
A
Abstract:
New N-hydroxyamides of n-alkyl carboxylic acids omega substituted with suitable tricyclic systems characterised by a central 7-membered ring, having activity as inhibitors of histone deacetylase (HDAC).

Inventors:
Guidi Antonio
Dimorous vine
Giannotti Danilo
Halmat Nicholas
Application Number:
JP2008501283A
Publication Date:
August 21, 2008
Filing Date:
March 13, 2006
Export Citation:
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Assignee:
Menarini International Operations Luxembourg Societe Anonima
International Classes:
C07D243/38; A61K31/5513; A61K31/553; A61K31/554; A61P1/16; A61P3/10; A61P29/00; A61P33/00; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D267/20; C07D281/16; C07D285/36; C07D291/08; C07D401/06; C07D471/04; C07D495/04
Domestic Patent References:
JPS53121780A1978-10-24
JPS5444693A1979-04-09
Attorney, Agent or Firm:
Jyohei Yamashita



 
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