Title:
N-ACETYL-D-HEXOSAMINE DERIVATIVE, ITS PRODUCTION, N-ACETYL-BETA-D-HEXOSAMINIDASE ACTIVITY-DETERMINING SUBSTRATE AND DETERMINING METHOD
Document Type and Number:
Japanese Patent JPH03215492
Kind Code:
A
Abstract:
NEW MATERIAL:A compound expressed by formula I (one of A1 and A2 is H and the other is OH; G is derivative of sugar or sugar excluding glucose).
EXAMPLE: A compound expressed by formula II.
USE: Used as a substrate for determination of N-acetyl-β-D-hexosaminidase activity.
PREPARATION: A D-hexosamine is acetylated and allowed to react with a thiol- based compound to obtain a N-acetyl-D-hexosamine-1-thio derivative. Next, said derivative is made to an oxazoline compound, then a resultant compound is subjected to a reaction with a derivative of a sugar or a sugar except glucose at a condition of 20-90°C.
Inventors:
OGAWA YOSHISUKE
ITO HIROSHI
CHIBA HIROSHI
SATO SHIGERU
MORITA SATOSHI
ITO HIROSHI
CHIBA HIROSHI
SATO SHIGERU
MORITA SATOSHI
Application Number:
JP684690A
Publication Date:
September 20, 1991
Filing Date:
January 16, 1990
Export Citation:
Assignee:
KURITA WATER IND LTD
International Classes:
C12Q1/34; C07H5/06; C07H5/10; C07H9/06; (IPC1-7): C07H5/06; C07H5/10; C07H9/06; C12Q1/34
Attorney, Agent or Firm:
Tsuyoshi Shigeno