Title:
N-アルカノイルフェニルアラニン誘導体
Document Type and Number:
Japanese Patent JP3727536
Kind Code:
B2
Abstract:
Compounds of formula (I) are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and /or damage are related to the binding of VCAM-1 to cells expressing VLA-4.
Inventors:
Chen, Lee
Guthrie, Robert William
Han, Thailand-Nan
Hull, Kenneth Gee
Sidri, Axalao
Tilly, Jefferson Wright
Guthrie, Robert William
Han, Thailand-Nan
Hull, Kenneth Gee
Sidri, Axalao
Tilly, Jefferson Wright
Application Number:
JP2000507644A
Publication Date:
December 14, 2005
Filing Date:
August 13, 1998
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/198; A61K31/33; A61K31/357; A61K31/36; A61K31/401; A61K31/41; A61K31/415; A61K31/4166; A61K31/42; A61K31/426; A61K31/44; A61K31/4409; A61K31/4418; A61K31/4427; A61K31/4439; A61K31/47; A61K31/496; A61K31/505; A61K31/519; A61K31/5375; A61K31/5377; A61P1/00; A61P11/06; A61P19/02; C07C233/81; C07C233/87; C07C235/40; C07C235/64; C07C235/82; C07C237/24; C07C255/41; C07C255/57; C07C271/22; C07C275/18; C07C275/24; C07C275/30; C07C275/60; C07C317/44; C07C317/50; C07C323/39; C07C323/60; C07C335/08; C07D207/16; C07D211/64; C07D213/81; C07D213/82; C07D213/89; C07D215/50; C07D217/26; C07D231/14; C07D233/32; C07D233/38; C07D239/28; C07D249/06; C07D257/04; C07D261/08; C07D261/18; C07D277/14; C07D277/20; C07D277/56; C07D295/08; C07D295/088; C07D295/14; C07D317/30; C07D317/68; C07D401/06; C07D487/04; (IPC1-7): C07C233/81; A61K31/198; A61K31/33; A61K31/36; A61K31/401; A61K31/41; A61K31/415; A61K31/4166; A61K31/42; A61K31/426; A61K31/44; A61K31/4409; A61K31/4439; A61K31/47; A61K31/505; A61K31/519; A61K31/5375; A61P1/00; A61P11/06; A61P19/02; C07C317/44; C07C317/50; C07C323/39; C07C323/60; C07C335/08; C07D207/16; C07D213/81; C07D213/82; C07D213/89; C07D215/50; C07D231/14; C07D233/32; C07D233/38; C07D239/28; C07D249/06; C07D257/04; C07D261/08; C07D277/20; C07D277/56; C07D295/08; C07D295/14; C07D317/68; C07D401/06; C07D487/04
Domestic Patent References:
| JP2001517246A | ||||
| JP2000515493A | ||||
| JP2001512137A | ||||
| JP2001512136A | ||||
| JP2003517424A | ||||
| JP2001512139A | ||||
| JP2002512625A |
Foreign References:
| WO1997023451A1 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda