To obtain a medicine participating in activation of T cell and mastocyte participating in immunization and allergic reaction, inhibiting tyrosine phosphatase which CD45 antigen has, having a new mechanism of action.
This N-arylthiooxamide derivative is represented by formula I [R1 is a 6-1C alkyl group, a 2-5C alkoxycarbonyl 1-5C alkyl group, a phenyl group substituted with a phenyl group or benzyloxy group, a thienyl 1-5C alkyl group, an adamanthyl methyl group, a 1-2-5C alkoxycarbonyl-4-piperidyl group, a phenyl imidazolyl group or a group of formula II (R is a hydrogen atom or a 2-5C alkoxycarbonyl group; R' is a 1-5C alkyl group); R2 is a phenyl group, a phenyl group which is substituted with 1-3 groups selected from a halogen atom, a 1-5C alkyl group, a 1-5C alkoxy group and a phenyl group or a naphthyl group].
KOBAYASHI YUIKO
HAMAGUCHI TAKUYA
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