Title:
N-GUANIDIONTHIOUREA SALT AND PRODUCTION OF 3-AMINO-5-MERCAPTO-1,2,4-TRIAZOLE
Document Type and Number:
Japanese Patent JP3032386
Kind Code:
B2
Abstract:
PURPOSE: To easily and safely produce the compound useful as a raw material for pharmaceuticals, agricultural chemicals, etc., by reacting a compound having thiocyanic acid group and aminoguanidine group or reacting a thiocyanic acid compound with an aminoguanidine compound in a polar solvent in the presence of an acid.
CONSTITUTION: An N-guanidinothiourea salt is produced by reacting a compound having thiocyanic acid group and aminoguanidine group (e.g. aminoguanidine thiocyanate) or reacting a compound having thiocyanic acid group (e.g. ammonium thiocyanate) with a compound having guanidine group (e.g. aminoguanidine bicarbonate) in the presence of an acid (e.g. hydrochloric acid) in a polar solvent (e.g. deionized water) under heating and refluxing for 1hr. The obtained N- guanidinothiourea salt is alkalinized with 50% aqueous solution of sodium hydroxide and made to react under heating and refluxing for 1.5hr to easily and safely obtain 3-amino-5-mercapto-1,2,4-triazole.
Inventors:
Takehiko Yoshie
Masanori Sasaki
Hiroshi Shibuchi
Yasushi Imai
Masanori Sasaki
Hiroshi Shibuchi
Yasushi Imai
Application Number:
JP21881092A
Publication Date:
April 17, 2000
Filing Date:
July 27, 1992
Export Citation:
Assignee:
Nippon Carbide Industry Co., Ltd.
International Classes:
C07D249/14; C07C337/06; (IPC1-7): C07D249/14; C07C337/06
Domestic Patent References:
| JP5247004A | ||||
| JP58193541A |
Other References:
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