Title:
過剰増殖性疾患の処置のためのErbBI型受容体チロシンキナーゼ阻害剤としてのN4-フェニルキナゾリン-4-アミン誘導体および関連化合物
Document Type and Number:
Japanese Patent JP5134548
Kind Code:
B2
Abstract:
This invention provides compounds of Formula (I), wherein B, G, A, E, R 1 , R 2 , R 3 , m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.
Inventors:
Lishika Toes, Joseph Py
Marma Setel, Fredrick Py
Chao, Jiang
Gureshuk, Julie Marie
Ryu, Waiton
Hennings, Di David
Marma Setel, Fredrick Py
Chao, Jiang
Gureshuk, Julie Marie
Ryu, Waiton
Hennings, Di David
Application Number:
JP2008541330A
Publication Date:
January 30, 2013
Filing Date:
November 15, 2006
Export Citation:
Assignee:
VentiRx Pharmaceuticals,Inc.
International Classes:
C07D401/14; C07D403/12; C07D403/14; C07D405/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D471/04; C07D495/04; C07D519/00; A61K31/517; A61K31/519; A61K31/5377; A61K31/541; A61P1/04; A61P1/18; A61P3/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/00; A61P19/02; A61P19/04; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP2005515176A | ||||
| JP2004517059A | ||||
| JP2002544196A | ||||
| JP2007502786A | ||||
| JP2004527486A |
Foreign References:
| WO2005007083A1 | ||||
| US20050059678 | ||||
| WO2002083622A1 |
Attorney, Agent or Firm:
Kuro Fukami
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Hisato Noda
Masayuki Sakai
Nobuo Arakawa
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Hisato Noda
Masayuki Sakai
Nobuo Arakawa