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Title:
ANTIINFLAMMATORY AGENT OR REGULATOR FOR MOTILITY OF DIGESTIVE TRACT
Document Type and Number:
Japanese Patent JPH0578254
Kind Code:
A
Abstract:

PURPOSE: To obtain an anti inflammatory agent or a regulator for motility of digestive tracts containing tetrahydro-WS9326A as an active ingredient.

CONSTITUTION: An antiinflammatory agent or a regulator for motility of digestive tracts containing a compound expressed by the formula [R1 is H or acyl; R2 is OH; R3 is carboxy or protected carboxy or R2 and R3 are mutually bound to form O-(C=O); R4 and R5 are OH or protected OH; R6 is OH, protected OH or lower alkoxy; the bond with the dotted line is single or double bond], preferably a compound in which R1 is phenyl(lower)alkanoyl group substituted with lower alkyl, especially 3-(2-pentylphenyl)propanoyl group; R2 and R3 are mutually bound to form O-(C=O); R4 to R6 are OH and bond with the dotted line is double bond as an active ingredient. The above-mentioned pharmaceutical is effective in preventing and treating various arthritides such as rheumarthritis, osteoarthritis, periarthritis humeroscapularis or cervical syndrome or further irritable bowel syndrome such as diarrhea or constipation.


Inventors:
FUJII TAKASHI
TOMOI MASAAKI
Application Number:
JP36103991A
Publication Date:
March 30, 1993
Filing Date:
December 16, 1991
Export Citation:
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Assignee:
FUJISAWA PHARMACEUTICAL CO
International Classes:
A61K38/04; A61P1/00; A61K38/00; A61P29/00; A61K38/08; A61P43/00; C07C237/42; C07K7/06; (IPC1-7): A61K37/02
Attorney, Agent or Firm:
Aoki High



 
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