PURPOSE: To obtain an anti inflammatory agent or a regulator for motility of digestive tracts containing tetrahydro-WS9326A as an active ingredient.
CONSTITUTION: An antiinflammatory agent or a regulator for motility of digestive tracts containing a compound expressed by the formula [R1 is H or acyl; R2 is OH; R3 is carboxy or protected carboxy or R2 and R3 are mutually bound to form O-(C=O); R4 and R5 are OH or protected OH; R6 is OH, protected OH or lower alkoxy; the bond with the dotted line is single or double bond], preferably a compound in which R1 is phenyl(lower)alkanoyl group substituted with lower alkyl, especially 3-(2-pentylphenyl)propanoyl group; R2 and R3 are mutually bound to form O-(C=O); R4 to R6 are OH and bond with the dotted line is double bond as an active ingredient. The above-mentioned pharmaceutical is effective in preventing and treating various arthritides such as rheumarthritis, osteoarthritis, periarthritis humeroscapularis or cervical syndrome or further irritable bowel syndrome such as diarrhea or constipation.
JP2008169195 | INSULINOTOPIC PEPTIDE DRUG COMBO USING CARRIER MATERIAL |
JPH09323940 | MEDICINE COMPOSITION |
WO/1997/041824 | ANTIANGIOGENIC PEPTIDES DERIVED FROM PLASMINOGEN |
TOMOI MASAAKI