Title:
NANOEMULSION VACCINES
Document Type and Number:
Japanese Patent JP2010195788
Kind Code:
A
Abstract:
To provide methods and compositions for the stimulation of immune responses.
Specifically, the methods and compositions are provided for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental pathogens. Accordingly, in some embodiments, the present invention provides nanoemulsion vaccines including a nanoemulsion and an inactivated pathogen or protein derived from the pathogen. The vaccines against a variety of environmental and human-released pathogens is provided. Here, immunogens are the compositions which are chosen from a group which consists of viruses, bacteria, fungi, and pathogen products originating in viruses, bacteria, or fungi.
Inventors:
BAKER JAMES R
HAMOUDA TAREK
HAMOUDA TAREK
Application Number:
JP2010051231A
Publication Date:
September 09, 2010
Filing Date:
March 09, 2010
Export Citation:
Assignee:
UNIV MICHIGAN
International Classes:
A61K39/00; A01N25/04; A61K9/00; A61K9/107; A61K39/02; A61K39/12; A61K39/39; A61K47/10; A61K47/18; A61K47/22; A61K47/24; A61K47/34; A61K47/44; A61P31/04; A61P31/10; A61P31/12; A61P37/04; C12N15/09
Domestic Patent References:
| JPH05294845A | 1993-11-09 | |||
| JPH06507172A | 1994-08-11 | |||
| JPH05508385A | 1993-11-25 | |||
| JPH10500686A | 1998-01-20 |
Foreign References:
| WO1997029773A1 | 1997-08-21 | |||
| WO1995011700A1 | 1995-05-04 | |||
| WO1999033459A1 | 1999-07-08 | |||
| US5700679A | 1997-12-23 |
Other References:
JPN7009001795; Ａｎｔｉｖｉｒａｌ ｃｈｅｍｉｓｔｒｙ ＆ ｃｈｅｍｏｔｈｅｒａｐｙ ２０００， Ｖｏｌ．１１， Ｎｏ．１, ｐａｇｅｓ ４１-４９
JPN6009015988; Ｊｏｕｒｎａｌ ｏｆ ｉｎｆｅｃｔｉｏｕｓ ｄｉｓｅａｓｅｓ １９９９， Ｖｏｌ．１８０， Ｎｏ．６, ｐａｇｅｓ １９３９-１９４９
JPN6009015989; Ｊｏｕｒｎａｌ ｏｆ ａｐｐｌｉｅｄ ｍｉｃｒｏｂｉｏｌｏｇｙ ２０００， Ｖｏｌ．８９， Ｎｏ．３, ｐａｇｅｓ ３９７-４０３
JPN6009015988; Ｊｏｕｒｎａｌ ｏｆ ｉｎｆｅｃｔｉｏｕｓ ｄｉｓｅａｓｅｓ １９９９， Ｖｏｌ．１８０， Ｎｏ．６, ｐａｇｅｓ １９３９-１９４９
JPN6009015989; Ｊｏｕｒｎａｌ ｏｆ ａｐｐｌｉｅｄ ｍｉｃｒｏｂｉｏｌｏｇｙ ２０００， Ｖｏｌ．８９， Ｎｏ．３, ｐａｇｅｓ ３９７-４０３
Attorney, Agent or Firm:
Hatsushi Shimizu