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Title:
NANOPARTICLE ARIPIPRAZOLE FORMULATION
Document Type and Number:
Japanese Patent JP2013136621
Kind Code:
A
Abstract:

To provide compositions comprising nanoparticle aripiprazole, or salts thereof or derivatives thereof, having improved bioavailability, faster rates of absorption and a faster onset of therapeutic effect and to provide the methods.

The compositions of the stable nanoparticle aripiprazole, or salts thereof of derivatives thereof include: (a) aripiprazole particles whose average effective particle sizes of less than about 2,000 nm; (b) at least one kind of surface stabilizers. Dosage forms thereof are also provided.


Inventors:
JENKINS SCOTT
MERISKO-LIVERSIDE ELAINE
Application Number:
JP2013042916A
Publication Date:
July 11, 2013
Filing Date:
March 05, 2013
Export Citation:
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Assignee:
ELAN PHARMA INT LTD
International Classes:
A61K31/496; A61K9/06; A61K9/107; A61K9/12; A61K9/14; A61K9/19; A61K9/20; A61K9/22; A61K9/48; A61K9/52; A61K31/5415; A61K31/551; A61K31/5513; A61K31/554; A61K45/00; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/22; A61K47/24; A61K47/26; A61K47/28; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61K47/44; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24
Domestic Patent References:
JP2004256555A2004-09-16
JPH04295420A1992-10-20
JP2002538199A2002-11-12
Foreign References:
WO2005041937A22005-05-12
WO2004006959A12004-01-22
WO2005000265A22005-01-06
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Ryuichi Inoue
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki