Title:
NANOSCALE PARTICLES FOR DELIVERING THERAPEUTIC AGENTS
Document Type and Number:
Japanese Patent JP2022078190
Kind Code:
A
Abstract:
To provide nanoscale particles for delivering therapeutic agents.SOLUTION: Provided is a nanoscale particle for delivering a therapeutic agent utilizing a prodrug containing a lipid moiety attached to a drug derivative such as an anticancer drug derivative via a linker containing a disulfide group. A synergistic therapeutic effect is generated from the combination of a plurality of modalities provided by the nanoparticle and/or a nanoparticle formulation.SELECTED DRAWING: Figure 1AB
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Inventors:
LIN WENBIN
DUAN XIAOPIN
CHRISTINA CHAN
HAN WENBO
DUAN XIAOPIN
CHRISTINA CHAN
HAN WENBO
Application Number:
JP2022032275A
Publication Date:
May 24, 2022
Filing Date:
March 03, 2022
Export Citation:
Assignee:
UNIV CHICAGO
International Classes:
A61K47/69; A61K9/107; A61K9/14; A61K31/122; A61K31/282; A61K31/337; A61K31/357; A61K31/365; A61K31/407; A61K31/437; A61K31/4375; A61K33/243; A61K47/14; A61K47/24; A61K47/28; A61K47/54; A61P35/00; A61P43/00
Domestic Patent References:
| JP2015527301A | 2015-09-17 |
Foreign References:
| WO2015069926A1 | 2015-05-14 |
Other References:
JOURNAL OF CONTROLLED RELEASE, vol. 208, JPN6021012404, 2015, pages 25 - 41, ISSN: 0005064767
THERANOTICS, vol. 6, no. 7, JPN6021012408, 28 April 2016 (2016-04-28), pages 1065 - 1074, ISSN: 0005064768
EUR.J.BIOMED.RES., vol. 2, no. 1, JPN6021012406, 31 January 2016 (2016-01-31), pages 8 - 15, ISSN: 0005064769
NATURE COM., vol. Vol.5, Article number: 4182, JPN6021012410, 2014, pages 1 - 11, ISSN: 0005064770
THERANOTICS, vol. 6, no. 7, JPN6021012408, 28 April 2016 (2016-04-28), pages 1065 - 1074, ISSN: 0005064768
EUR.J.BIOMED.RES., vol. 2, no. 1, JPN6021012406, 31 January 2016 (2016-01-31), pages 8 - 15, ISSN: 0005064769
NATURE COM., vol. Vol.5, Article number: 4182, JPN6021012410, 2014, pages 1 - 11, ISSN: 0005064770
Attorney, Agent or Firm:
Akira Shimoda
Kenichiro Akao
Kenichiro Akao
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