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Title:
NAPHTHALENE DERIVATIVES
Document Type and Number:
Japanese Patent JP2008050361
Kind Code:
A
Abstract:

To provide pharmaceuticals in treating or preventing a disease or condition in which cannobinoid receptor activation plays a role.

The present invention relates to naphthalene derivatives of formula (I), wherein X is S, S(O), S(O)2, S(O)2NH, P(O)OCH3, P(O)OH, NH, N(CH3), NHC(O)NH, C(O), C(O)O, NHC(O), CH(OH), CH=N, CH=CH, CH2NH, C(=NH); R1 is aryl or heteroaryl; R2 is hydrogen, OR4 or NR5R6 and the other variables are as defined in the description, and the preparation thereof.


Inventors:
BRAIN CHRISTOPHER THOMAS
CULSHAW ANDREW JAMES
DZIADULEWICZ EDWARD KAROL
SCHOPFER ULRICH
Application Number:
JP2007236718A
Publication Date:
March 06, 2008
Filing Date:
September 12, 2007
Export Citation:
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Assignee:
NOVARTIS AG
International Classes:
C07C43/23; A61K31/085; C07D249/08; A61K31/10; A61K31/12; A61K31/136; A61K31/15; A61K31/155; A61K31/165; A61K31/166; A61K31/167; A61K31/17; A61K31/18; A61K31/185; A61K31/192; A61K31/198; A61K31/216; A61K31/222; A61K31/235; A61K31/275; A61K31/277; A61K31/41; A61K31/415; A61K31/4164; A61K31/4184; A61K31/4196; A61K31/4245; A61K31/433; A61K31/445; A61K31/47; A61K31/472; A61K31/495; A61K31/496; A61K31/4965; A61K31/5375; A61K31/662; A61K45/00; A61P1/04; A61P7/10; A61P9/10; A61P17/02; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P19/04; A61P19/06; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P27/06; A61P29/00; A61P37/02; A61P37/08; A61P41/00; A61P43/00; C07C41/16; C07C43/20; C07C45/46; C07C45/68; C07C49/84; C07C59/31; C07C65/40; C07C67/39; C07C69/017; C07C69/14; C07C69/157; C07C69/63; C07C69/712; C07C69/76; C07C69/94; C07C205/45; C07C217/76; C07C217/94; C07C225/22; C07C231/02; C07C233/65; C07C235/84; C07C243/14; C07C243/28; C07C251/24; C07C255/56; C07C257/18; C07C259/18; C07C273/02; C07C275/32; C07C303/34; C07C303/38; C07C311/08; C07C311/13; C07C311/29; C07C311/37; C07C315/02; C07C317/22; C07C317/34; C07C319/14; C07C323/21; C07C323/38; C07C323/41; C07C323/42; C07D215/08; C07D215/20; C07D215/26; C07D215/32; C07D215/48; C07D215/58; C07D217/02; C07D217/04; C07D217/16; C07D231/12; C07D233/60; C07D235/16; C07D235/26; C07D235/30; C07D257/04; C07D271/10; C07D271/12; C07D285/14; C07D295/08; C07D295/092; C07D295/096; C07D295/10; C07D295/12; C07D521/00; C07F9/12; C07F9/30; C07F9/32; C07F9/572; C07F9/60
Domestic Patent References:
JP2004514663A2004-05-20
Foreign References:
DE1016717B1957-10-03
US1874581A1932-08-30
GB1200273A1970-07-29
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi