Title:
NATURAL COLLAGENASE INHIBITOR BY RECOMBINED DNA TECHNIQUE
Document Type and Number:
Japanese Patent JPS61227786
Kind Code:
A
Abstract:
This invention refers to the novel 184 amino acid sequence of a human natural inhibitor of collagenases (NIC) and its production. It also refers to novel DNA and RNA sequences, plasmids, transformed prokaryotic and eukaryotic cells, the production of NIC amino acid sequences with and without glycosylation, and compositions containing these novel NICs to treat diseases that incorporate collagenase-type metalloproteinases as part of the disease process.
Inventors:
UIRIAMU ARAN GAROUEI
PATORISHIA MERII KURISORUDO
KEISU GURAHAMU MATSUKURAGU
PATORISHIA MERII KURISORUDO
KEISU GURAHAMU MATSUKURAGU
Application Number:
JP783086A
Publication Date:
October 09, 1986
Filing Date:
January 17, 1986
Export Citation:
Assignee:
SEARLE & CO
International Classes:
C12N15/09; A61K38/55; A61P43/00; C07H21/02; C07K14/005; C07K14/195; C07K14/81; C12N1/00; C12N5/10; C12N9/99; C12N15/81; C12P21/00; A61K38/00; C12R1/19; C12R1/865; C12R1/91; (IPC1-7): A61K35/74; A61K37/64; C07H21/02; C07H21/04; C07K15/04; C12N1/00; C12N5/00; C12N9/99; C12N15/00; C12P21/00; C12R1/19; C12R1/865; C12R1/91
Attorney, Agent or Firm:
Asamura Akira