Title:
新規のラパコン化合物およびその使用方法
Document Type and Number:
Japanese Patent JP2009538298
Kind Code:
A
Abstract:
The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or to inhibit proliferation of cancer or precancerous cells. The naphthoquinone derivatives of the present invention are related to the compound known as ß-lapachone (3,4-dihydro-2,2-dimethyl-2H- naphtho(l ,2-b)pyran-5 ,6-dione).
Inventors:
Ashwell,mark
Tandon, Mannish
Lapierre, Jean-Mark
Ants, Said
David, Bensel
Lee, Chang Jay.
Tandon, Mannish
Lapierre, Jean-Mark
Ants, Said
David, Bensel
Lee, Chang Jay.
Application Number:
JP2009511995A
Publication Date:
November 05, 2009
Filing Date:
August 21, 2006
Export Citation:
Assignee:
Acre Incorporated
International Classes:
C07D497/10; A61K31/438; A61K31/444; A61K31/4545; A61K31/55; A61K45/00; A61P35/00; A61P35/02
Domestic Patent References:
| JP2006508147A | 2006-03-09 |
Foreign References:
| WO2006128120A2 | 2006-11-30 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita