Title:
新規17βルパン誘導体
Document Type and Number:
Japanese Patent JP2011511812
Kind Code:
A
Abstract:
The invention relates to 17β lupane derivatives of formula (I): wherein R1 and X are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infection by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
Inventors:
Monet, Christoph
Liu, Vinkan
Harab, Lillian
Turcot, Natalie
Denise, Real
Carl, Poisson
Nguyen-Ba, Paul
Bubenik, Monica
Chang Chun Kong, Laval
Liu, Vinkan
Harab, Lillian
Turcot, Natalie
Denise, Real
Carl, Poisson
Nguyen-Ba, Paul
Bubenik, Monica
Chang Chun Kong, Laval
Application Number:
JP2010546189A
Publication Date:
April 14, 2011
Filing Date:
February 13, 2009
Export Citation:
Assignee:
Bairokem Pharma Inc.
International Classes:
C07J63/00; A61K31/56; A61K45/00; A61P31/18
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita