Title:
NOVEL APIXABAN PREPARATION
Document Type and Number:
Japanese Patent JP2023121748
Kind Code:
A
Abstract:
To provide an amorphous apixaban, a composition containing an amorphous apixaban and an amorphizer, and an apixaban-containing solid preparation that contains the amorphous apixaban or the composition and has excellent leachability and stability.SOLUTION: An amorphous apixaban has a crystal apixaban content of 5% or less relative to the total amount of apixaban.SELECTED DRAWING: None
Inventors:
SASAKI MASARU
MIYATA KEISUKE
TANIGUCHI YUKI
MAEJIMA KEIICHI
HIRAI YOSUKE
ONUKI TETSUYA
KOYAMA HARUKI
MIYATA KEISUKE
TANIGUCHI YUKI
MAEJIMA KEIICHI
HIRAI YOSUKE
ONUKI TETSUYA
KOYAMA HARUKI
Application Number:
JP2023025496A
Publication Date:
August 31, 2023
Filing Date:
February 21, 2023
Export Citation:
Assignee:
FUJI CHEM IND CO LTD
International Classes:
C07D471/04; A61K9/14; A61K9/20; A61K31/4545; A61K47/38; A61P7/02
Attorney, Agent or Firm:
Arga Patent Office